By Özge ÖzkayaGenetic Predisposition to Endometriosis
By Özge Özkaya
Certain genetic polymorphisms, called SNPs, in the ESR2 and CYP19A1 genes, were more prevalent among patients with endometriosis compared to women without the disease according to a study by researchers in Poland. A better understanding of the genetic mechanisms underlying the…
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By Dr. Youngran ParkNovel inhibitors of estrogen biosynthesis
By Dr. Youngran Park
Endometriosis is a chronic benign disease which is estrogen-dependent. Estradiol creates a positive feedback loop with the synthesis of pro-inflammatory mediators, which sustains further disease establishment and causes the pain symptoms. However, hormone therapies do not cure definitively endometriosis, because…
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